Radiomics-Based Outcome Prediction in Transarterial Radioembolization (TARE) of Hepatic Malignancies: A Systematic Review and Quality Appraisal

Background

Transarterial radioembolization (TARE) with Yttrium-90 (90Y) microspheres is an established locoregional treatment for primary and secondary hepatic malignancies. Treatment response is heterogeneous, and accurate pre-procedural prediction of outcome remains a clinical challenge. Radiomics, defined as the high-throughput extraction of quantitative imaging features, may capture subvisual tumour heterogeneity that might be predictive of response, therefore enabling individualised patient selection and treatment planning.