Molecular imaging and radionuclide therapy
Papillary Thyroid Microcarcinomas Detected by Nuclear Medicine Imaging: Distinct Clinicopathological Features Compared with Conventional Modalities
Par Oğuz SH, Çınar İ, Ertürk B et 5 autres.
Contenu en anglais
Résumé
Objectives
Papillary thyroid carcinomas detected by nuclear medicine imaging techniques may have a worse prognosis than those identified by conventional methods. However, it remains unclear whether this applies to papillary thyroid microcarcinomas (PTMCs).
Methods
Patients diagnosed with PTMC at Hacettepe University Faculty of Medicine between 2008 and 2020 were categorized into three groups: (1) incidental PTMCs (Inc-PTMC; n=249), (2) non-incidental PTMCs (NonInc-PTMC; n=134), and (3) PTMCs detected by nuclear medicine imaging methods (NM-PTMC; n=24). Tumor pathological characteristics, including multifocality, extrathyroidal extension, vascular invasion, and lymph node involvement, were analyzed. Logistic regression analysis was performed to assess the association between detection method and tumor aggressiveness while adjusting for potential confounders.