International Journal of Health Economics and Social Sciences
Effect of Calendula officinalis L. extract emulgel on TNF-α and VEGF levels in UV-B-exposed male Wistar rats
Par Puty Annisa Prilina, Joko Wahyu Wibowo et Prasetyowati Subchan.
Contenu en anglais
Résumé
Background
Ultraviolet B (UV-B) exposure triggers photoaging through inflammatory mediators such as tumor necrosis factor-α (TNF-α) and vascular endothelial growth factor (VEGF). Calendula officinalis L. contains flavonoids, triterpenoids, and carotenoids with potential anti-inflammatory and angiogenic activity. This study evaluated the effect of Calendula officinalis L. extract emulgel on TNF-α and VEGF levels in UV-B-exposed Wistar rats.