Protective Effects of Rutin and Hesperidin on Cisplatin-Induced Testicular Dysfunction in Rats: Rutin and Hesperidin in Testicular Toxicity

Background

Cisplatin is a common chemotherapeutic agent that is known to cause testicular toxicity by oxidative stress, inflammation, and apoptosis, resulting in impaired reproductive function in male patients. Natural flavonoids such as rutin and hesperidin have been shown to have potential protective effects due to their antioxidant properties.