Efficacy of Submucosal Hydrocortisone Injection Versus Normal Saline in Third Molar Surgery

Background

It is well recognized that corticosteroids lessen edema, fluid transudation, and inflammation. These substances, which are released by the adrenal glands, are important for sustaining metabolism. Their anti-inflammatory properties are among their most important functions. Methodology: A double-blind, randomized, controlled study. Twenty patients requiring surgical removal impacted third molar participated in the trial. The patients were split into two groups of 10 at random: Group I received a submucosal injection of hydrocortisone, and following the establishment of local anesthetic, Group II (the placebo group) was given a submucosal injection of normal saline. Postoperative sequelae were assessed on the second and seventh days after surgery.