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Pharmacology Role in Diabetic Retinopathy: A Review of Pathophysiology, Pharmacological Targets and Therapeutic Approaches
Par Gajendra Jayant, Pooja Gourav, Omkar Rajput et 2 autres.
Contenu en anglais
Résumé
Background
Diabetic retinopathy (DR) is a microvascular and neurodegenerative complication of diabetes and remains a leading cause of preventable visual impairment in working-age adults. Because the number of people living with diabetes continues to grow, the absolute burden of DR is expected to rise for decades.
Objective
This review summarises the molecular and cellular mechanisms that drive DR, maps them onto established and emerging pharmacological targets, and appraises the clinical evidence for current drug-based management.