The familial hereditary linked genes (BRCA1 & BRCA2) in first degree relatives of prostatic cancer patients attending urology department of kosti teaching hospital from 1.2.2023 to 1.8.2023

Introduction

Carcinoma of the prostate is a critical public health problem in Sudan, and its spectrum my encountered from serious complications up to death with chronic disability to families, and a major challenge on health incomes. Inherited variants in particular genes, such as BRCA1 and BRCA2 account for some cases of hereditary prostate cancer. Men with variants in these genes have a high risk of developing prostate cancer and, in some cases, other cancers during their lifetimes.