Association of plasma fibrinogen level and c-reactive protein level with severity of preeclampsia

Background

Preeclampsia is a pregnancy disorder that is a leading cause of maternal and perinatal morbidity and mortality, characterized by elevated blood pressure and proteinuria after 20 weeks of gestation. In preeclampsia there is a shift in the hemostatic balance towards a prothrombotic state together with changes in endothelial function, and C-reactive protein (CRP) is a sensitive inflammatory marker that rises in response to inflammation or tissue injury.