Oxaprozin-Based Amide Derivatives as Multifunctional Agents: Synthesis, Characterization, and Comprehensive Biological Profiling

Background/Objectives: Inflammation plays a role at multiple levels, contributing to tumorigenesis, cellular proliferation, cell survival, and metastasis. The established link between chronic inflammation and tumor development has shifted the therapeutic focus toward nonsteroidal anti-inflammatory drugs, which exert their effects primarily through cyclooxygenase inhibition.