Codonopsis tangshen Attenuates Age-Related Pulmonary Fibrosis through Senescence and Gut–Lung Axis Modulation

Background

Cellular senescence is a critical driver of chronic inflammation, tissue remodeling, and progressive fibrosis during the aging process. Codonopsis tangshen Oliv. is a widely used medicinal and edible homologous plant in traditional Chinese medicine; however, its pharmacological effects on natural aging and age-related pulmonary fibrosis, as well as the underlying mechanisms, are still not fully elucidated.

Methods