Journal of Respiration
Challenges in Diagnosing Primary Ciliary Dyskinesia and the Role of Nasal Nitric Oxide Testing: A Single Center Experience
Par Mikiyas Teshome Desta, Claire L. Keating, Aliva De et 1 autres.
Contenu en anglais
Résumé
Rationale
Nasal nitric oxide (nNO) measurement is a recommended noninvasive screening tool for primary ciliary dyskinesia (PCD), but studies examining its real-world performance are limited, and integration of PCD diagnostic pathways varies across centers.
Objective
The objective of this study was to evaluate the diagnostic utility of nNO, describe phenotypic profiles of patients with low and normal NO levels, and highlight the existing challenges in diagnosing PCD.