Thermo-Mechanical Ablation (TMA®) with Tixel® C for Evaporative Dry Eye Associated with Meibomian Gland Dysfunction: A Multicenter, Open-Label, Single-Arm, Exploratory Clinical Study

Background

Tixel® C (Novoxel Ltd., Netanya, Israel) is a thermomechanical system that conducts heat to soft tissue via a titanium tip heated to 400 °C and has been used for skin rejuvenation, including the eyelids. Its efficacy for dry eye disease (DED) and meibomian gland dysfunction (MGD) has been reported, but it has not been evaluated in Japanese patients.