Diagnostics
Weight-Independent Cardioprotective Effects of Physical Activity in Patients with Myocardial Infarction
Par Corina Cinezan, Camelia Bianca Rus, Timea Claudia Ghitea et 2 autres.
Contenu en anglais
Résumé
Background
Physical activity is a key modifiable determinant of cardiovascular risk, yet whether its protective association with coronary artery disease (CAD) severity in patients with myocardial infarction (MI) is mediated by body mass index (BMI) remains uncertain.
Methods
This cross-sectional study included 294 adults admitted with MI and angiographically confirmed MI. Daily preadmission physical activity, as a score, BMI, cardiovascular risk factors and angiographic CAD extent (single-, double-, or triple-vessel disease) were analyzed. Multivariable ordinal logistic regression assessed independent associations of preadmission physical activity with CAD severity. Mediation analysis evaluated BMI as an intermediary using non-parametric bootstrap resampling with 2000 iterations and 95% confidence intervals (CIs).