A Computational Analysis of Diagnostic Misrecognition in Co-Occurring Primary Headache Disorders: Prime Encoding of ICHD3 Criteria Reveals 72 Potentially Spurious Diagnoses

Background/Objectives: In clinical circumstances with more than one headache disorder, misrecognition can occur if each headache disorder is not separately and individually evaluated. For example, consider the case of a patient with baseline tension-type headaches lasting hours who now develops cluster headaches with nausea. Merging the characteristics of both disorders may yield the illusion of migraine. Do these types of misrecognitions occur necessarily because of ICHD3 criteria? Are there combinations of ICHD3 criteria, if any, which yield this type of misrecognition? This work seeks to determine whether a new, unintended diagnosis can be arrived at when one merges two primary ICHD3 diagnoses.