Current Issues in Molecular Biology
Follistatin-Like Protein 1 Contributes to Acute Traumatic Spinal Cord Injury by Enhancing Neuroinflammation Through the Modulation of Interferon Regulatory Factor 5-Mediated Macrophage Activation
Par Yixing Luo, Shaozhou Ni, Lü Peng et 4 autres.
Contenu en anglais
Résumé
Background and Purpose: Follistatin-like protein 1 (Fstl1) is a secreted glycoprotein with context-dependent inflammatory activity. We investigated whether Fstl1 is a reproducible feature of traumatic spinal cord injury (SCI) and whether it regulates macrophage activation through interferon regulatory factor 5 (IRF5).