Real-World Management and Survival Outcomes in Patients with Primary or Recurrent Retroperitoneal Liposarcoma: A Single-Center Retrospective Cohort Study

Background/Objectives: Histological subtype and resection completeness are established prognostic factors in retroperitoneal liposarcoma, but evidence often derives from resected primary disease. We characterized management and post-referral survival in a referral cohort.

Methods

We retrospectively analyzed 61 patients managed from May 2015 to September 2025. Overall survival (OS) was measured from first presentation at our center. Kaplan–Meier and exploratory Cox analyses were performed, allowing the association between tumor diameter and mortality to vary over time.