Microcystic Adnexal Carcinoma of the Head and Neck: Diagnostic Work-Up and Contemporary Treatment Strategies—A Narrative Review

Background

Microcystic adnexal carcinoma (MAC) is a rare cutaneous adnexal malignancy characterized by slow clinical growth but pronounced local aggressiveness, extensive subclinical infiltration, and a propensity for perineural invasion. Owing to its rarity and often inconspicuous clinical presentation, diagnosis and treatment remain challenging, particularly in the anatomically complex head and neck region.