Thyroid Cancer Incidence in North-East Spain, 2002–2021: A Population-Based Study

Background/Objectives: The incidence of thyroid cancer (TC) has increased worldwide over recent decades, particularly for well-differentiated histological subtypes, a trend largely attributed to overdiagnosis. Given potential geographical differences, this study analyzed TC incidence and temporal trends in the province of Girona, Spain, between 2002 and 2021.

Methods

We conducted a cross-sectional study using data from the Girona Cancer Registry. Crude incidence rates (CRs), age-standardized incidence rates using the 2013 European (ASRe) and the 1960 World (ASRw) standard populations were calculated per 100,000 person-years. Temporal trends were assessed via the annual percentage change (APC) using generalized linear models.