Antibiotics
Association Between Surgical Timing and In-Hospital Mortality in Infective Endocarditis: A Retrospective Single-Centre Study
Par Adelina Maria Radu, Irina Florentina Talpoși, Raluca Elena Țoțoiu et 12 autres.
Contenu en anglais
Résumé
Introduction
Infective endocarditis (IE) remains associated with high mortality, and the optimal timing of surgery in patients without an urgent indication remains uncertain. We evaluated the association between surgical timing and in-hospital mortality.
Methods
We retrospectively studied 100 adults with definite IE admitted during 2020–2025 at a tertiary care centre in Bucharest, Romania. The ECHO score incorporated aetiology, blood culture time to positivity, vegetation size, and embolisation or surgical indication. Surgical timing was categorised as study-specific descriptive bins: <7 days, 7–14 days, or >14 days after hospital admission. The primary outcome was in-hospital mortality.