From Evidence to Practice: A Behaviourally Informed Multidisciplinary Strategy to Increase Cefazolin Prophylaxis in Joint Arthroplasty Patients with Penicillin Allergy Labels

Background

Cefazolin is recommended for surgical prophylaxis in most patients with penicillin allergy labels (PALs) but concerns over beta-lactam cross-reactivity often limit use. We evaluated a behaviourally informed, multidisciplinary antimicrobial stewardship strategy on cefazolin utilisation among patients with PALs undergoing joint arthroplasty.