Clinical ophthalmology
The Paul Glaucoma Implant versus the Ahmed and Baerveldt Glaucoma Implants: A Systematic Review and Bayesian Network Meta-Analysis
Par Mohamed Nasser Elshabrawi, Bara M. Hammadeh, Ayodeji Arobo et 5 autres.
Contenu en anglais
Résumé
Purpose
To compare the efficacy and safety of the Paul Glaucoma Implant (PGI) with those of the two established glaucoma drainage devices, the Ahmed Glaucoma Valve (AGV) and the Baerveldt Glaucoma Implant (BGI).
Methods
PubMed, Embase, Scopus, Web of Science, Cochrane CENTRAL, ClinicalTrials.gov, ScienceDirect and Google Scholar were searched. Eligible studies were randomised or comparative observational studies reporting outcomes in patients who received the PGI alongside a concurrent AGV or BGI comparator. The primary outcomes were intraocular pressure (IOP) reduction, surgical success rate, and reduction in glaucoma medications. A Bayesian network meta-analysis was performed, with treatment ranking summarized by surface under the cumulative ranking curve (SUCRA). Quality assessment and evidence certainty was performed using the Cochrane Risk of Bias tool and GRADE framework respectively.