Reference Intervals of Hematological Parameters Among Healthy Pregnant Women in Eastern Sudan: A Prospective Longitudinal Cohort Study

Background

Pregnancy induces maternal hematological adaptations. Because these shifts are influenced by environmental, nutritional, and ethno-geographic variations, relying on international adult reference intervals (RIs) may increase the risk of diagnostic misclassification. Given the scarcity of context-specific reference intervals in Sudan, this study aimed to establish the localized, trimester-specific complete blood count (CBC) RIs for healthy pregnant women in Eastern Sudan.