Preprints.org
Obstructive Sleep Apnea Is Associated with Adverse Cardiovascular Events Related to Sleep Blood Pressure
Par Castriotta RJ, Hermida RC, Smolensky MH et 1 autres.
Contenu en anglais
Résumé
Background
Obstructive sleep apnea (OSA) causes increased sleep systemic systolic blood pressure (SBP) and cardiovascular (CV) risk.
Methods
This secondary analysis encompassed data of 2,065 Spanish polysomnography-confirmed OSA hypertensives (61±11.9 years, 79.5% male) and 32,471 Spanish non-OSA hypertensives (60.2±14.0 years, 51% male) from the Hygia Project. Annually throughout the 5.1-year median follow-up, they underwent comprehensive clinical evaluation and 48-h ambulatory blood pressure (BP) monitoring, with bed and wake-up times diary-recorded to calculate individualized awake and sleep BP means and sleep-time relative declines.