Anwendungsgebiete
Vasostrict® is indicated to increase blood pressure in adults with vasodilatory shock (e.g., post-cardiotomy or sepsis) who remain hypotensive despite fluids and catecholamines.
Gegenanzeigen
Vasostrict® is contraindicated in patients with known allergy or hypersensitivity to 8-L-arginine vasopressin or chlorobutanol.
Warnhinweise und Vorsichtsmaßnahmen
5.1Worsening Cardiac Function Use
in patients with impaired cardiac response may worsen cardiac output.
Wechselwirkungen
7.1Catecholamines Use
with catecholamines is expected to result in an additive effect on mean arterial blood pressure and other hemodynamic parameters.
7.2Indomethacin Use
with indomethacin may prolong the effect of Vasostrict® on cardiac index and systemic vascular resistance [see Clinical Pharmacology ( 12- 12.3)].
7.3Ganglionic Blocking Agents Use
with ganglionic blocking agents may increase the effect of Vasostrict® on mean arterial blood pressure [see Clinical Pharmacology ( 12- 12.3)].
7.4Furosemide Use
with furosemide increases the effect of Vasostrict® on osmolar clearance and urine flow [see Clinical Pharmacology ( 12- 12.3)].