Anwendungsgebiete
ANECTINE is indicated in adults and pediatric patients:
- as an adjunct to general anesthesia
- to facilitate tracheal intubation
- to provide skeletal muscle relaxation during surgery or mechanical ventilation. ANECTINE is a depolarizing neuromuscular blocker indicated in adults and pediatric patients:
- as an adjunct to general anesthesia ( 1 )
- to facilitate tracheal intubation ( 1 )
- to provide skeletal muscle relaxation during surgery or mechanical ventilation ( 1 ).
Gegenanzeigen
ANECTINE is contraindicated in patients with:
- Known or suspected genetic susceptibility to malignant hyperthermia [see WARNINGS, Malignant Hyperthermia ( 5.5 ), CLINICAL PHARMACOLOGY, Pharmacogenomics ( 12.5 )]
- Skeletal muscle myopathies [see WARNINGS, Ventricular Dysrhythmias, Cardiac Arrest, and Death From Hyperkalemic Rhabdomyolysis in Pediatric Patients ( 5.1 )]
- Known hypersensitivity to succinylcholine [see Warnings and Precautions (5.2) ] .
- After the acute phase of injury following major burns, multiple trauma, extensive denervation of the skeletal muscle, or upper neuron injury because succinylcholine administered to such individuals may result in severe hyperkalemia, which may result in cardiac arrest [see Warnings and Precautions (5.4) ] .
- Skeletal muscle myopathies ( 4 )
- Known hypersensitivity to succinylcholine ( 4 )
- After the acute phase of injury following major burns, multiple trauma, extensive denervation of skeletal muscle, or upper motor neuron injury ( 4 )
- Known or suspected genetic susceptibility to malignant hyperthermia ( 4 )
Warnhinweise und Vorsichtsmaßnahmen
- Anaphylaxis : Severe anaphylactic reactions to neuromuscular blocking agents, including succinylcholine, have been reported. Some cases have been life-threatening and fatal. Take necessary precautions, such as the immediate availability of appropriate emergency treatment ( 5.2 ).