Neurogastroenterology and motility
A Genome-Wide Meta-Analysis of Functional Dyspepsia in 1,168,899 Individuals Implicates Immune Pathways in Disease Susceptibility
Von Díaz-Muñoz C, Broeders B, Bonfiglio F und 17 weiteren.
Inhalt auf Englisch
Abstract
Background
Functional dyspepsia (FD) affects over 7% of the global population, impairing quality of life and driving significant healthcare burden. Although genetic contributions to FD pathophysiology have been suspected, large, well-powered genetic studies remain limited. We aimed to identify FD genetic risk factors and implicated biological pathways.