Scientifica
Comparison Between Oculoplastic Surgeons and Two Large Language Models in the Nonsurgical Management of Thyroid Eye Disease: A Questionnaire-Based Cross-Sectional Study
Von Hui S, Luo L, Hou Z und 1 weiteren.
Inhalt auf Englisch
Abstract
Background
Thyroid eye disease (TED) presents heterogeneous clinical manifestations requiring nuanced, individualized management. Large language models (LLMs) have shown potential in clinical reasoning, but their consistency with physician decision-making in nonsurgical TED management remains unclear.
Methods
A structured 19-item questionnaire covering medical, injection-based, and radiotherapeutic treatments for TED was distributed to 17 oculoplastic surgeons across the Asia-Pacific region. Responses were binarized (1 = selected, 0 = not selected) and compared with standardized outputs from GPT and Gemini. Jaccard and cosine similarity indices were calculated to quantify the alignment between physicians and LLMs.