Surgical case reports
A Case of Primary Leiomyoma of the Chest Wall Showing High Uptake on FDG-PET
Von Sakaguchi T, Takahashi M, Cho S und 2 weiteren.
Inhalt auf Englisch
Abstract
Introduction
Primary leiomyoma of the chest wall is a rare entity. We report a case of primary chest wall leiomyoma with intense uptake on fluorodeoxyglucose PET (FDG-PET), requiring differentiation from malignancy.
Case presentation
An 82-year-old man with a history of asbestos exposure underwent annual chest CT surveillance. A 19-mm nodule was newly identified on the right chest wall and had not been present on CT the previous year. Although the lesion had well-defined margins on CT, FDG-PET demonstrated intense uptake with a maximum standardized uptake value of 11.8, raising suspicion for malignancy. Surgical resection was performed for diagnostic and therapeutic purposes. Histopathological examination revealed fascicular proliferation of spindle-shaped cells. Immunohistochemical analysis suggested a smooth muscle tumor, and retention of BRCA1-associated protein 1 and methylthioadenosine phosphorylase excluded mesothelioma. Based on these findings, the tumor was diagnosed as a primary leiomyoma of the chest wall.