Advances in therapy
Perinatal Outcomes of Pleuro-Amniotic Shunting in Isolated Pleural Effusions: Systematic Review and Meta-analysis
Von Amorim EL, Araujo Júnior E, da Silva Lourenço MC und 7 weiteren.
Inhalt auf Englisch
Abstract
Introduction
Pleuro-amniotic shunting has been proposed for fetal pleural effusion, although its safety and efficacy remain uncertain. Therefore, we aimed to evaluate the perinatal outcomes of the fetal therapy for isolated pleural effusion through a systematic review and single-arm meta-analysis.
Methods
PubMed/MEDLINE, Embase, Scopus, and Cochrane Central were searched for studies reporting outcomes of fetuses undergoing pleuro-amniotic shunting for isolated pleural effusion. The primary outcomes were overall survival and resolution of fetal hydrops. Single-arm random-effects meta-analyses were performed to estimate pooled event rates with 95% confidence intervals (CI).