Korean journal of radiology
Radiofrequency Ablation for Low-Risk T1N0M0 Papillary Thyroid Carcinoma: A Systematic Review and Meta-Analysis
Von Lee MK, Ha EJ, Lee JY und 1 weiteren.
Inhalt auf Englisch
Abstract
Objective
To evaluate the efficacy and safety of ultrasound (US)-guided radiofrequency ablation (RFA) for low-risk T1N0M0 papillary thyroid carcinoma (PTC), with emphasis on T1a versus T1b outcomes and longitudinal volume regression.
Materials and methods
MEDLINE, EMBASE, Cochrane Library, and KoreaMed databases were searched for studies published between January 2000 and March 2025. Both single-arm and comparative studies were eligible when RFA outcome data could be extracted independently. Thirty-five studies (9,787 tumors) were included in the analysis. Pooled estimates for complete disappearance, persistent tumors, disease progression, and complication rates were calculated using random-effects models. The volume-reduction ratio (VRR) was assessed at sequential follow-up intervals. Subgroup analyses were used to compare the outcomes for T1a and T1b PTCs.