Seroprevalence and trends of transfusion-transmissible infections among blood donors in the Volta Region, Ghana: A four-year retrospective study

Background

Blood transfusion is a life-saving intervention; however, transfusion-transmissible infections (TTIs) such as human immunodeficiency virus (HIV), hepatitis B virus (HBV), hepatitis C virus (HCV), and syphilis remain major public health concerns, particularly in low- and middle-income countries. This study assessed the seroprevalence and temporal trends of TTIs among blood donors in the Volta Region of Ghana and to identify the demographic factors associated with seropositivity.