PloS one
Behavioural correlates of higher 12-month myopia progression in a high-risk vietnamese schoolchild cohort and the limits of cross-school prediction
Von Nguyen SH, Nguyen DP und Tran TT.
Inhalt auf Englisch
Abstract
Background
The clinical interpretation of myopia progression depends on the measurement interval, refractive protocol, and the population from which the analytic sample was selected.
Methods
We performed a secondary analysis of 200 myopic schoolchildren from 10 schools who had been selected for the intervention stage of a parent study after rapid progression (>=1.0 D/year). Parent-study documentation indicates a 12-month follow-up and progression calculated from the change in spherical-equivalent refraction (SE). The de-identified analytic archive retained only three 12-month progression values (1.25, 1.50, and 1.75 D); it did not retain paired eye-level refractions or sufficient metadata to independently verify the exact discretization mechanism or cycloplegic status of both examinations. We therefore contrasted a study-specific higher progression category (>=1.50 D; 99/200, 49.5%) with 1.25 D. A parsimonious logistic model used school-clustered robust standard errors (n = 199 complete cases; 99 outcomes; 10 predictor coefficients), and prediction was evaluated by leave-one-school-out cross-validation.