Southern medical journal
Antibiotic Stewardship in Nonoperative Facial Trauma: Necessary or Not?
Von Isaac JI und Castro Garcia JA.
Inhalt auf Englisch
Abstract
Objective
Closed facial fractures are common and often treated nonoperatively. Routine systemic antibiotic prophylaxis is controversial because infection rates are low and antibiotics can cause harm. We assessed whether prophylactic antibiotics reduce infectious complications in closed, nonoperative facial fractures.
Methods
A systematic review was conducted of adults with closed, nonoperative facial fractures (emergency department, inpatient, intensive care unit). PubMed, Scopus, and Google Scholar were searched from inception through September 19, 2025. Studies compared systemic prophylaxis versus none and/or ≤24 hours versus >24 hours.