Extended spectrum beta-lactamase Klebsiella pneumoniae (ESBL-KP) bloodstream infection outbreak in a Neonatal Intensive Care Unit (NICU) in Bangui, Central African Republic (CAR)

Background

Multidrug-resistant organism (MDRO) outbreaks in NICUs cause high mortality and strain hospital resources globally, particularly in low-income countries (LICs). In Central African Republic (CAR), limited data on antimicrobial resistance indicate high rates of MDRO. We describe an outbreak of Extended Spectrum Beta-Lactamase-producing Klebsiella pneumoniae (ESBL-KP) in a Ministry of Health (MoH) hospital NICU in Bangui, supported by Médecins Sans Frontières (MSF).