Prophylactic Immediate Lymphatic Reconstruction for the Prevention of Secondary Lymphedema: A Systematic Review and Meta-Analysis of Comparative Studies

Background

Secondary lymphedema remains a frequent and debilitating complication of axillary and inguinal lymph node dissection within oncological settings. Prophylactic lymphovenous shunting (LVS) delivered as immediate lymphatic reconstruction (ILR) has emerged as a strategy to preserve lymphatic continuity and reduce postoperative lymphedema. This systematic review and meta-analysis evaluated the effectiveness of prophylactic LVS across oncologic indications.