Viruses
Study of Molecular Genetic Characteristics of Influenza A(H1N1) Viruses Identified During Monitoring in Kazakhstan (2023–2026)
Von N. G. Klivleyeva, Т. И. Глебова, A. M. Baimukhametova und 8 weiteren.
Inhalt auf Englisch
Abstract
Background/Objectives: Seasonal influenza threatens global public health through rapid mutations. This study evaluated the prevalence and molecular-genetic characteristics of seasonal influenza viruses circulating in Kazakhstan during the 2023–2026 epidemic seasons.
Methods
Nasopharyngeal swabs (n = 1756) and serum samples (n = 718) were screened using RT-qPCR, HI, and ELISA assays. Selected A(H1N1)pdm09 isolates underwent full-length HA and NA gene next-generation sequencing, followed by phylogenetic and phenotypic analyses.