Beyond Breslow Thickness: Reproducibility and Histopathologic Concordance of Ultra-High-Frequency Ultrasound in Primary Cutaneous Melanoma

Background

Ultra-high-frequency ultrasound (UHFUS) provides high-resolution assessment of superficial skin lesions, but evidence in melanoma has largely focused on preoperative thickness estimation. We evaluated the reproducibility of a structured UHFUS assessment and its histopathologic concordance in primary cutaneous melanoma.