Telemedicine-Enabled Medication Optimization for Adults with Polypharmacy: A Systematic Review and Implications for Saudi Vision 2030 Healthcare Transformation

Background/Objectives: Polypharmacy may increase the risk of medication discrepancies, drug–drug interactions, potentially inappropriate prescribing, nonadherence, adverse drug events, and avoidable healthcare use. Telemedicine may improve access to medication review, particularly for older adults, people with multimorbidity, and geographically underserved populations. This review evaluated the effectiveness, safety, acceptability, and implementation requirements of telemedicine-enabled medication optimization and considered implications for Saudi Vision 2030.