[2026-10-07] Effect of Clinical Practice Guideline for Early Mobilization on Limb Muscle Strength in Critically Ill Patients

Background

Intensive care unit (ICU)-acquired weakness is a significant complication affecting approximately 34.1% of ICU patients, leading to muscle atrophy, prolonged hospitalization, and increased mortality. Early mobilization (EM) is a critical nursing practice to mitigate these effects. Despite its benefits, standardized guidelines are often underutilized due to safety concerns and the limited availability of clinical protocols.